FAQ

Find clear answers about Targeted Radionuclide Therapy (TRT), how to access treatment, and how the Oncidium foundation and its programs work. If you are missing any information or want to know more about our foundation, our projects, or radiotheranostics, please do not hesitate to contact us.

  • All themes
  • About the Oncidium foundation
  • For patients & families
  • Patient Advocacy
  • Support & donations
  • Targeted Radionuclide Therapy (TRT) & radiotheranostics
  • RLT Connect
  • Does advocacy mean promoting TRT for every patient?

    No. TRT is not suitable for every patient or every cancer.

    Oncidium’s advocacy work focuses on access and healthcare systems. Decisions about whether TRT is appropriate for an individual patient remain with qualified healthcare professionals and the patient.

  • What are the priorities of the Patient Advocacy & Policy Department?

    The department works around three main priorities:

    • awareness and acceptability;
    • evidence generation;
    • governance and policy integration.

    Across all three, the aim is to better understand patient needs and the barriers that affect access to TRT.

  • What is the Experts by Experience Task Force?

    The Experts by Experience Task Force brings together patients, caregivers and healthcare professionals to help guide the work of Oncidium’s Patient Advocacy & Policy Department.

    Members help identify important questions, highlight gaps in information and provide perspectives from different healthcare systems and lived experiences.

  • Does Oncidium speak on behalf of patients?

    Our approach is to work alongside patients rather than only speaking for them.

    Patients, caregivers and healthcare professionals contribute directly through initiatives such as the Experts by Experience Task Force and other patient engagement activities.

  • What is health policy?

    Health policy refers to the decisions, rules and frameworks that influence how healthcare is organised, funded and delivered.

    For TRT, this may include questions related to reimbursement, infrastructure, referral pathways and how new treatments are integrated into cancer care.

  • What is patient advocacy?

    Patient advocacy aims to make sure that the experiences, needs and priorities of patients are considered in discussions and decisions that affect their care.

    At Oncidium, this means working alongside patients and caregivers to better understand barriers to TRT and bringing these insights into wider conversations about access and healthcare policy.

  • Where does my donation go?

    Donations support the foundation's mission to improve access to Targeted Radionuclide Therapy, including the RLT-Connect treatment donation program and its education and access work.

  • What is the Tackle Cancer Challenge?

    The Tackle Cancer Challenge is the Oncidium foundation's global sports challenge. Participants walk, run, or cycle to raise awareness and funds that support access to treatment through RLT-Connect.

  • How can I support the Oncidium foundation?

    There are several ways to help. You can make a donation, join the Tackle Cancer Challenge, become an Ambassador, or partner with us as an organisation. Every contribution helps improve access to TRT for patients who need it.

  • What should I prepare before contacting a treatment center?

    Have your most recent medical documents ready in electronic format.
    This usually includes :

    • your latest medical reports,
    • your imaging and imaging protocols (PET scan, MRI, CT, X-rays),
    • your pathology analyses (biopsy, surgical specimen, puncture),
    • and your blood test results.

    Having these ready helps the center understand your situation quickly.

  • Can a patient apply for treatment or a donated dose directly?

    No. Patients cannot register themselves or request a dose. The request must come from a healthcare professional at a hospital that is able to deliver the treatment. If you think TRT may be relevant, speak with your medical team.

  • How much does TRT cost, and is it reimbursed?

    Cost and reimbursement vary widely by country, center, and indication. In some places TRT is reimbursed, in others it is paid out of pocket. If cost is the barrier and the necessary infrastructure exists, ask your healthcare professional about RLT-Connect, our treatment donation program.

  • Is TRT available in my country?

    Availability depends on local approval, infrastructure, and reimbursement, which vary widely from one country to another. The treatment center map is a useful starting point, and the center can confirm what applies to your situation.

  • How do I find a Targeted Radionuclide Treatment center near me?

    Use our interactive treatment center map to search by country, cancer type, and imaging. Centers register themselves to appear on the map, so always confirm availability, eligibility, and reimbursement directly with the center and your physician.

  • How can I access Targeted Radionuclide Therapy (TRT)?

    Start by discussing it with your oncologist or nuclear medicine specialist, who can assess whether it may be relevant for you and refer you if appropriate. You can also use our treatment center map to see where TRT may be available.

  • What is 177Lu (lutetium-177)?

    Lutetium-177 (177Lu) is a therapeutic radionuclide widely used in Targeted Radionuclide Therapy. It is attached to a targeting molecule so that radiation is delivered mainly to cancer cells that carry the matching target.

  • Is TRT safe, and what are the side effects?

    TRT is designed to focus radiation on cancer cells while limiting exposure to healthy tissue. Like any cancer treatment, it can cause side effects, which vary depending on the therapy, the cancer, and the individual. Your medical team is the right source to explain the possible benefits and risks in your specific situation.

  • Which cancers can be treated with TRT?

    TRT is currently used or being studied in several cancers. The most established examples include prostate cancer, often using a target called PSMA, and neuroendocrine tumours (NET), using a form known as PRRT. Research continues into other indications. Whether TRT is appropriate depends on the individual diagnosis and imaging, and is always decided with the medical team.

  • What is the difference between TRT, RLT, and radiotheranostics?

    These terms are closely related.

    • Radiotheranostics is the overall approach that pairs imaging and treatment through the same target.
    • Targeted Radionuclide Therapy (TRT) is the treatment itself, and it is the term the Oncidium foundation now uses.
    • Radioligand therapy (RLT) is an earlier name for the same idea that is still common in the field and in program names such as RLT-Connect.
  • What is radiotheranostics?

    Radiotheranostics combines diagnostics and therapy through the same molecular target. An imaging agent, used with PET or SPECT, shows whether the target is present in the body (See it), and when appropriate, a therapeutic version delivers treatment to those same cells (Treat it). This is the principle behind Targeted Radionuclide Therapy (TRT).

  • What is Targeted Radionuclide Therapy (TRT)?

    Targeted Radionuclide Therapy (TRT) is a cancer treatment that delivers radiation directly to cancer cells while sparing much of the surrounding healthy tissue. It pairs a targeting molecule, which recognises a specific feature on cancer cells, with a radionuclide. TRT is part of a wider approach called radiotheranostics, summed up as "See it. Treat it.": the same targeting principle is used first with imaging to locate the disease, and then to treat it. It is used or studied in several cancers, including prostate cancer and neuroendocrine tumours. Whether it is suitable for a patient is always decided with the medical team.

  • Does the Oncidium foundation provide or prescribe treatment?

    No. The Oncidium foundation is a facilitator. It does not diagnose, prescribe, or administer treatment, and it does not select or endorse treatment centers. All medical decisions stay with the patient and their care team.

  • Where is the Oncidium foundation based?

    The Oncidium foundation is based in Belgium and operates internationally, with an ambassador network active across many countries.

  • What is RLT-Connect?

    A collaborative platform implemented by the Oncidium foundation to enable radioligand therapy treatments for patients who cannot afford it in countries that already have the infrastructure to deliver such therapies.

    The RLT-Connect platform connects healthcare practitioners and Radioisotope companies that donate Radioisotope doses to provide radioligand therapy for those who cannot otherwise afford it.

  • What is the Oncidium foundation’s role in this project?

    The RLT-Connect platform is an Oncidium foundation initiative. Oncidium is acting as a facilitator, connecting and establishing an effective, operational ecosystem among HCPs, Radioisotope companies, and local radiopharmacies to provide donated doses to patients who cannot afford treatment costs. Oncidium’s role is limited to:

    • Facilitating the connections between HCPs and Radioisotope suppliers;
    • Evaluating clinical sites' requests according to pre-defined eligibility criteria for centers and the Ethics charter;
    • Setting up and hosting the online RLT-Connect platform
  • What are the roles of the other stakeholders (clinical sites, Radioisotope suppliers, local radiopharmacies)?

    Clinical Sites

    • Selection of patients and creation of paperwork for treatment access: early access, compassionate use, expanded access, etc.
    • Submission of cases on online platform
    • Contact with local Radiopharmacy for the logistics, Labeling and QC.
    • Feedback on treatment outcomes

    Local Radiopharmacies

    • Importation process, customs clearance, inland transportation.
    • Labeling and QC
    • Delivery at clinical site

    Isotope suppliers

    • Dose donations
    • Definition of number of doses to be donated each year
  • Who can register on the platform?

    • Healthcare professionals working in centers that already use 177Lu and that have experience in treating patients with 177Lu radiopharmaceuticals. Thus, patients cannot register themselves to seek a dose.
    • Radioisotopes suppliers that wish to donate radioisotopes (including dose donation, shipment, and importation taxes).
  • What is being donated?

    The RLT-Connect is currently donating 177LuCl (lutetium-177 (177Lu) chloride).
  • Who can benefit from the donation?

    Patients who cannot afford the therapy, mainly from low- and medium-income countries, where there is no reimbursement. Dose distribution is limited for each country and will be allocated evenly across the world.
  • Are costs of diagnostic tests, doses for Imaging, related costs of hospitalization covered by Oncidium? If not, who covers them?

    Currently, RLT-Connect is only mediating about donated doses for treatment, not Imaging or diagnostic tests.

    The objective of the program is to create a connection between the parties, and everyone involved is donating something. The supplier donates the doses, the Radiopharmacy usually covers the costs of logistics/import and labelling, and the hospital covers the costs of Imaging and hospitalization.

  • Is it possible to go to another country for the treatment?

    Yes, it is possible, where cross-border healthcare is allowed. Anyway, the receiving hospital needs to be registered on the RLT-Connect platform. Also, it is the treating hospital who needs to make the request. Oncidium may finance the travel of patience who are in financial need.
  • Who can request a treatment/dose?

    Healthcare professionals, in countries where the necessary infrastructure is already implemented to deliver the doses to the patients. Moreover, patients cannot register themselves to seek a dose, the request should come from the hospital that can deliver the treatment.

    What’s more, once the donation is approved, doses are donated by the Radioisotopes Companies and directly to the centers and will not transit through the Oncidium foundation.

  • Who is responsible for organizing the dose delivery?

    The Hospital that is requesting the dose. The order of donated dose by the Radiopharmacy, follows the same process as commercial ones.

    Once the donation is approved, doses are donated by the radioisotopes companies directly to the hospitals and will not transit through the Oncidium foundation.

  • How many doses can a patient expect to receive within the donation program?

    Once a case is accepted and validated for donation to a patient, the foundation commits to providing the necessary doses, including a full treatment cycle personalized to the patient’s needs. Additionally, patients who have already received doses and require additional ones may also benefit from the donation in case they meet the eligibility criteria established for the program. On the other hand, if a patient does not respond to the treatment, the doses will be reallocated to another patient in need, ensuring efficient use of resources.
  • What if a patient does not respond to the treatment or needs fewer doses than the requested amount?

    The physician responsible for the request will change the request on the platform to the actual need. The excess doses will be redirected to another patient in need, ensuring efficient use of resources.

  • Who will validate the treatment/dose donation?

    An Ad Hoc committee set up by the Oncidium foundation, composed of field specialists.

  • What is the timing for the donation to arrive?

    Usually, we must request the suppliers at least 20 days in advance. Nevertheless, suppliers may have different requirements.

  • Who is responsible for the labelling?

    The labelling will be carried out by the Radiopharmacy center that already works with the hospitals. It must be indicated in the registration form.
  • Who is responsible for the importation and logistics process?

    The importation and logistics of the 177LuCl dose will follow the same process as already done by your center for commercial doses. The Oncidium foundation does not intermediate these processes.

  • How can I request a donation?

    1. Register your center here https://www.oncidiumfoundation.org/registration/clinical/;
    2. Receive the confirmation of the registration request by email;
    3. If your center registration is approved, you will receive by email a contract and the RLT-Connect ethical charter to be signed by the physician and the hospital director.
    4. An additional document will also be attached to the local Radiopharmacy your hospital is working with for signature.
    5. Once the contracts are signed, you will be able to request a dose.
    6. To request a dose, log into the platform: https://www.oncidiumfoundation.org/;
    7. Click on “Create a request”;
    8. Answer the qualifying criteria form and submit it.
    9. After careful consideration of the request, you will receive a response within 15 working days, indicating either a positive or negative return.
  • Can private centers also sign the agreement?

    Yes. All centers that are actively treating patients with radiopharmaceuticals 177Lu, 131I (or other radioisotopes under request) can sign the agreement

  • Is it possible to set up partnerships or events with other organizations?

    The agreement with Oncidium includes the non-exclusivity article. Hence, both Oncidium and the hospital are free to establish an agreement offering related services to other healthcare professionals and institutions.

  • How does the involvement of local Radiopharmaceutical providers work?

    Local radiopharmacies are indicated at the moment of registration by the healthcare professional who signs up on the platform. They can be internal radiopharmacies to the hospital or collaborating external structures.
    The Radiopharmacy will be requested to sign an RLT-Connect agreement specific to radiopharmacies.