Novel radiopharmaceutical pair detects and treats melanoma; study shows potential for broad application in solid tumors.

14 June 2022 – Reports and Proceedings , Society of Nuclear Medicine and Molecular Imaging

A newly developed small-molecular radiopharmaceutical pair has successfully visualized and treated melanoma in a preclinical study.
“The results of this study highlight the strong potential of using [11C]1 and [211At]1 as theranostic agents for the management of GRM-positive tumors.” said Lin Xie, MD, PhD, a senior researcher in the Department of Advanced Nuclear Medicine Sciences at the National Institutes for Quantum and Radiological Science and Technology.

Credit : Lin Xie, Masayuki Hanyu, Masayuki Fujinaga, Lulu Zhang, Yiding Zhang, Kuan Hu, Mori Wakana, Katsuyuki Minegishi, Kotaro Nagatsu, Kazunori Kawamura, and Ming-Rong Zhang, Department of Advanced Nuclear Medicine Sciences, National Institute of Radiological Sciences, National Institutes for Quantum and Radiological Science and Technology, Chiba, Japan.

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