177Lu-Ludotadipep (177Lu-FC705) is a 177Lu-labeled analogue of 177Lu-Vipivotide targeting PSMA. In order to increase stability and specificity of the molecule, and to reduce side-effects, albumin was introduced in the structure, creating a so-called second generation of radiolabeled PSMA targeting therapeutics.
177Lu-Ludotadipep completed Phase I in 2022.

Target/Mechanism: PSMA

Carrier/Ligand: PSMA

Radiation Type: beta electrons (β)

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