lymphoma

DESCRIPTION

Lymphoma is a cancer of the lymphatic system. It develops in lymphocytes, which are a type of white blood cell. These cells help fight disease in the body and play an essential role in the body’s immune defenses. It most often spreads to the liver, bone marrow, or lungs. There are two main types of lymphoma: Hodgkin (HL) and non-Hodgkin lymphoma (NHL) (the most common type).

Chemotherapy is often used in the treatment of lymphoma. For some types of lymphoma, chemotherapy drugs are often combined with targeted treatments, such as Rituximab^®. It has been noted that NHL becomes progressively chemoresistant while remaining responsive to external beam radiation therapy. Because of their remarkable effectiveness, radiolabeled tracers and drugs for imaging and therapy has been approved for use in patients with NHL. These drugs have proven to be remarkably effective and safe.

Sources: Medical News Today, NIH.gov, Lymphoma-action.org

APPROVED TREATMENTS

⁹⁰Y-Ibritumomab Tiuxetan (Zevalin®) (NHL-diffuse large B-cell lymphoma(DLBCL))

IN DEVELOPMENT

¹⁷⁷Lu-Lilotomab satetraxetan (Betalutin) (Non-Hodgkin’s lymphoma) 

¹³¹I-Apamistamab (Iomab-B™) (acute myeloid lymphoma-myelodysplastic syndrome-Hodgkin’s disease – NHL)  

STATISTICS

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PATIENT ASSOCIATIONS

Europe: Action Lymphome Wallonie Bruxelles – ALWB (BEL), AEAL (SPA), Bulgarian Lymphoma Patients’ Association (BGR), Croatian Association of Leukemia and Lymphomas (HRV), Deutsche Leukamie & Lymphom-Hilfe eV Germany (DEU), Drustvo bolnikov z limfomom Slovenia (SVN), France Lymphome Espoir (FRA), GAL (ITA), HEMA (MKD), Hodgkin and non-Hodgkin vzw (BEL), Linfovita (ITA), LPSA (LVA), Lyle (DNK), Lymfklierkanker Vereniging Vlaanderen (LVV) (BEL), Lymfom Help Czech Republic (SZE)

Worldwide: Cutaneous Lymphoma Foundation, Lymphoma Research Foundation, Patients Against Lymphoma 

Africa: Ensemble Contre le Lymphome (MAR)

APAC:  House086 (CHN), Hong Kong Blood Cancer Foundation (HKG), Lymphoma Australia (AUS)

Middle East: The Flute of Light (ISR)

LATAM: ABRALE (BRA), Asociación Gerardo Alfaro Mexico (MEX), FUNALINH Mexico (MEX), Linfomas Argentina (ARG), The Myeloma, Lymphoma & Leukaemia Foundation of Barbados (BRB)

CLINICAL TRIALS

Lymphoma ¹⁷⁷Lu based clinical trials

Lymphoma ¹³¹I based clinical trials

Lymphoma ⁹⁰Y based clinical trials

Lymphoma ²¹¹At based clinical trials

*non-exhaustive list

ABOUT LYMPHOMA

Lymphoma – National Cancer Society

Lymphoma; Patient Version – National cancer Institute NIH